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End-tidal CO2 Monitoring During CPR

Question Type:
Intervention
Full Question:
In infants and children in cardiac arrest (P), does does adjustment of chest compression technique to achieve a specific ETCO2
threshold (I), compared with compared with not using ETCO2 to adjust chest compression technique (C), change survival to 180 days with good neurological outcome, the likelihood of survival to discharge, ROSC (O)?
Consensus on Science:
We did not identify any evidence to address the important outcome of survival to hospital discharge or the critical outcome of neurologically intact survival. For the important outcome of ROSC, we identified very-low-quality evidence (downgraded for very serious indirectness and imprecision) from 1 pediatric animal RCT study that showed ETCO2-guided chest compressions are as effective as standard chest compressions optimized by marker, video, and verbal feedback.(Hamrick 2014, e000450)
Treatment Recommendation:
The confidence in effect estimates is so low that the panel decided a recommendation was too speculative.
CoSTR Attachments:
Peds 872 Grade.pdf    

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